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Assessment of vaccination strategies against highly pathogenic avian influenza in China
Honglei SUN,Jinhua LIU
《农业科学与工程前沿(英文)》 2014年 第1卷 第4期 页码 277-281 doi: 10.15302/J-FASE-2014036
关键词: highly pathogenic avian influenza vaccine vaccination control
Avian influenza A: an avian influenza virus from low pathogenic to highly pathogenic
William J. Liu, Haixia Xiao, Lianpan Dai, Di Liu, Jianjun Chen, Xiaopeng Qi, Yuhai Bi, Yi Shi, George F. Gao, Yingxia Liu
《医学前沿(英文)》 2021年 第15卷 第4期 页码 507-527 doi: 10.1007/s11684-020-0814-5
关键词: H7N9 HPAIV epidemiology clinical features pathogenesis hemagglutinin immunity vaccine
Research progress on human infection with avian influenza H7N9
Xiaoxin Wu, Lanlan Xiao, Lanjuan Li
《医学前沿(英文)》 2020年 第14卷 第1期 页码 8-20 doi: 10.1007/s11684-020-0739-z
Jiao HU,Xiufan LIU
《农业科学与工程前沿(英文)》 2016年 第3卷 第1期 页码 11-24 doi: 10.15302/J-FASE-2016092
关键词: avian influenza virus H9N2 H5N1 novel viruses public health
null
《医学前沿(英文)》 2013年 第7卷 第3期 页码 333-344 doi: 10.1007/s11684-013-0275-1
This study reports the first death caused by a novel avian influenza A (H7N9) virus in Zhejiang Province, China. The patient had chronic hepatitis B and history of exposure to poultry. The patient initially complained of diarrhea and influenza-like symptoms on March 7 and 14 respectively. The disease progressed to severe pneumonia, sustained hypoxia, and coagulation abnormalities. The patient died on March 27 because of respiratory failure, multiple organ failure, and disseminated intravascular coagulation without oseltamivir treatment. This H7N9 virus from Zhejiang is highly similar to isolates obtained from Shanghai, Jiangsu, Anhui, etc. Analysis of hemagglutinin, neuramidinase, and matrix genes indicated that the isolates share the same avian origin, have low virulence, and are sensitive to oseltamivir, but are resistant to adamantine. Only the isolate that caused the fatality exhibited substitution of Q226I in the HA gene, which indicates a potentially enhanced human affinity. The secondary transmission rate was 1.6% (2/125). Only two health workers presented with influenza-like symptoms, and they subsequently tested negative for H7N9 RNA. In conclusion, underlying disease, late diagnosis, and untimely antiviral treatment are possible high-risk factors for infections and death caused by the low-pathogenicity avian influenza A (H7N9). Person-to-person transmission of the H7N9 virus was not detected among close contacts, but such transmission should be investigated in the future. Expanding and enhancing surveillance will help in the early discovery and diagnosis of suspected cases, which will reduce the number of severe cases and deaths.
关键词: avian influenza A (H7N9) virus epidemiology contacts person-to-person transmission
Inactivation and risk control of pathogenic microorganisms in municipal sludge treatment: A review
《环境科学与工程前沿(英文)》 2022年 第16卷 第6期 doi: 10.1007/s11783-021-1504-5
• Diversity and detection methods of pathogenic microorganisms in sludge.
关键词: Sludge treatment Pathogenic microorganisms Inactivation mechanisms Exposure risks Land application
IN VITRO ACTIVITY OF EXTRACTS OF FIVE MEDICINAL PLANT SPECIES ON PLANT PATHOGENIC FUNGI
《农业科学与工程前沿(英文)》 2021年 第8卷 第4期 页码 635-644 doi: 10.15302/J-FASE -2020343
The antifungal effectiveness of extracts of five medicinal plant species was determined. The inhibitory activity of extracts of Eucalyptus tereticornis, Xanthium sibiricum, Artemisia argyi, Tupistra chinensis and Pyrola calliantha were evaluated against the mycelial growth of the plant pathogenic fungi Aspergillus niger, Botrytis cinerea, Penicillium digitatum, P. expansum, P. italicumand Rhizopus stolonifer. All plant extracts were prepared at 60°C using solvents (either water, 50% ethanol (v/v), 95% ethanol (v/v), ethyl acetate or petroleum ether). Fungicidal effects of all plants tested were confirmed. Different extracts from the same plant species gave different degrees of inhibition. All aqueous extracts had weak or no activity on all fungi tested. Ethyl acetate and 95% ethanol extracts from T. chinensis rhizomes gave greater inhibition and a broader spectrum inhibition than the other extracts. T. chinensis may have potential as a new natural fungicide and may be used for the preservation of agricultural and forestry products such as fruits and vegetables.
关键词: Botrytis cinerea / food preservation / plant diseases / plant pathogenic fungi / Tupistra chinensis
Research progress in pathogenic genes of hereditary non-syndromic mid-frequency deafness
null
《医学前沿(英文)》 2016年 第10卷 第2期 页码 137-142 doi: 10.1007/s11684-016-0449-8
Hearing impairment is considered as the most prevalent impairment worldwide. Almost 600 million people in the world suffer from mild or moderate hearing impairment, an estimated 10% of the human population. Genetic factors play an important role in the pathogenesis of this disorder. Hereditary hearing loss is divided into syndromic hearing loss (associated with other anomalies) and non-syndromic hearing loss (not associated with other anomalies). Approximately 80% of genetic deafness is non-syndromic. On the basis of the frequency of hearing loss, hereditary non-syndromic hearing loss can be divided into high-, mid-, low-, and total-frequency hearing loss. An audiometric finding of mid-frequency sensorineural hearing loss, or a “bowl-shaped” audiogram, is uncommon. Up to now, merely 7 loci have been linked to mid-frequency hearing loss. Only four genetic mid-frequency deafness genes, namely, DFNA10 (EYA4), DFNA8/12 (TECTA), DFNA13 (COL11A2), DFNA44 (CCDC50), have been reported to date. This review summarizes the research progress of the four genes to draw attention to mid-frequency deafness genes.
关键词: hereditary non-syndromic hearing loss mid-frequency hearing loss deafness genes
《环境科学与工程前沿(英文)》 2021年 第15卷 第3期 doi: 10.1007/s11783-020-1356-4
•Bacterial concentrations from eight stages were 104–105copies/m3.
关键词: Size distribution Airborne bacteria Biological diversity Human pathogenic bacteria Composting plants
Seroprevalence of influenza viruses in Shandong, Northern China during the COVID-19 pandemic
《医学前沿(英文)》 2022年 第16卷 第6期 页码 984-990 doi: 10.1007/s11684-022-0930-5
关键词: influenza virus seroprevalence antibody COVID-19 cross-sectional study
Innate and adaptive T cells in influenza disease
null
《医学前沿(英文)》 2018年 第12卷 第1期 页码 34-47 doi: 10.1007/s11684-017-0606-8
Influenza is a major global health problem, causing infections of the respiratory tract, often leading to acute pneumonia, life-threatening complications and even deaths. Over the last seven decades, vaccination strategies have been utilized to protect people from complications of influenza, especially groups at high risk of severe disease. While current vaccination regimens elicit strain-specific antibody responses, they fail to generate cross-protection against seasonal, pandemic and avian viruses. Moreover, vaccines designed to generate influenza-specific T-cell responses are yet to be optimized. During natural infection, viral replication is initially controlled by innate immunity before adaptive immune responses (T cells and antibody-producing B cells) achieve viral clearance and host recovery. Adaptive T and B cells maintain immunological memory and provide protection against subsequent infections with related influenza viruses. Recent studies also shed light on the role of innate T-cells (MAIT cells, gd T cells, and NKT cells) in controlling influenza and linking innate and adaptive immune mechanisms, thus making them attractive targets for vaccination strategies. We summarize the current knowledge on influenza-specific innate MAIT and gd T cells as well as adaptive CD8+ and CD4+ T cells, and discuss how these responses can be harnessed by novel vaccine strategies to elicit cross-protective immunity against different influenza strains and subtypes.
关键词: influenza innate T cells CD4+ and CD8+ T cells vaccination
ACTIVITY OF EXTRACTS OF FIVE MEDICINAL PLANT SPECIES ON PLANT PATHOGENIC FUNGI
Shufeng YAO, Jiali XU, Haibo ZHANG, Hong GAO, Shibin SHANG, Dan WANG
《农业科学与工程前沿(英文)》 2021年 第8卷 第4期 页码 635-644 doi: 10.15302/J-FASE-2020343
关键词: Botrytis cinerea food preservation plant diseases plant pathogenic fungi Tupistra chinensis
Compiling of comprehensive data of human infections with novel influenza A (H7N9) virus
null
《医学前沿(英文)》 2013年 第7卷 第3期 页码 275-276 doi: 10.1007/s11684-013-0285-z
Yulu Wang, Dan Hu, Yanling Wu, Tianlei Ying
《医学前沿(英文)》 2020年 第14卷 第2期 页码 149-159 doi: 10.1007/s11684-020-0764-y
关键词: influenza virus neutralizing antibody hemagglutinin globular head region trimeric interface
Global influenza surveillancewith Laplacianmultidimensional scaling
Xi-chuan ZHOU,Fang TANG,Qin LI,Sheng-dong HU,Guo-jun LI,Yun-jian JIA,Xin-ke LI,Yu-jie FENG
《信息与电子工程前沿(英文)》 2016年 第17卷 第5期 页码 413-421 doi: 10.1631/FITEE.1500356
标题 作者 时间 类型 操作
Assessment of vaccination strategies against highly pathogenic avian influenza in China
Honglei SUN,Jinhua LIU
期刊论文
Avian influenza A: an avian influenza virus from low pathogenic to highly pathogenic
William J. Liu, Haixia Xiao, Lianpan Dai, Di Liu, Jianjun Chen, Xiaopeng Qi, Yuhai Bi, Yi Shi, George F. Gao, Yingxia Liu
期刊论文
Research progress on human infection with avian influenza H7N9
Xiaoxin Wu, Lanlan Xiao, Lanjuan Li
期刊论文
Endemicity of H9N2 and H5N1 avian influenza viruses in poultry in China poses a serious threat to poultry
Jiao HU,Xiufan LIU
期刊论文
The first avian influenza A (H7N9) viral infection in humans in Zhejiang Province, China: a death report
null
期刊论文
Inactivation and risk control of pathogenic microorganisms in municipal sludge treatment: A review
期刊论文
The size distribution of airborne bacteria and human pathogenic bacteria in a commercial composting plant
期刊论文
ACTIVITY OF EXTRACTS OF FIVE MEDICINAL PLANT SPECIES ON PLANT PATHOGENIC FUNGI
Shufeng YAO, Jiali XU, Haibo ZHANG, Hong GAO, Shibin SHANG, Dan WANG
期刊论文
Recent advances in “universal” influenza virus antibodies: the rise of a hidden trimeric interface in
Yulu Wang, Dan Hu, Yanling Wu, Tianlei Ying
期刊论文